CrossRef API retrieved 12 valid DOIs but confirms Reference 12 mismatch concern

Source type: obs · Harvested: 2026-05-04 · Original date: 2026-05-04T02:16:27.854Z Metadata: {"project":"oncology-fih-research/oncology-fih-research","type":"discovery","obs_id":65306}


obs/65306 · discovery · 2026-05-04T02:16:27.854Z

CrossRef API retrieved 12 valid DOIs but confirms Reference 12 mismatch concern

Switching from PubMed to CrossRef API proved dramatically more successful for automated DOI retrieval, with 12 of 17 references achieving high-confidence matches (scores 72-121). The CrossRef bibliographic search used comprehensive query strings combining titles, journals, years, and authors, which improved matching accuracy compared to PubMed’s title-only approach. However, the results validate the Opus review’s critical warning about Reference 12: CrossRef matched “Wages Chiuzan Engel” authors with JCO Precis Oncol 2024 to a DIFFERENT article about toxicity handling (DOI 10.1200/po.23.00441), not the cited “Innovative dose-escalation designs” article. This low match score (46.5) and title mismatch strongly suggests the cited Reference 12 article does not exist as described in the manuscript, supporting the LLM-fabrication hypothesis. Additionally, References 13, 14, and 19 retrieved alternative versions (plain language summaries, conference abstracts, book chapters) rather than the original peer-reviewed articles, indicating these DOIs will require manual correction. The successful retrieval of 12 correct DOIs provides a foundation for P0 fix #2, but References 12-14 and 19 need manual verification and correction before submission.

Concepts: [“gotcha”,“problem-solution”,“what-changed”]

Facts: [“CrossRef bibliographic search successfully retrieved DOIs for 12 of 17 references with match scores above 70”,“Reference 12 matched to DOI 10.1200/po.23.00441 (score 46.5) with title “Handling Incomplete or Late-Onset Toxicities” not “Innovative dose-escalation designs"",“References 13, 14, 19 also returned incorrect DOIs due to title/author similarity: plain language summaries, symposium abstracts, or book chapters instead of original journal articles”,“High-confidence matches include Nat Biotechnol 2014 (score 98.7), JAMA 2004 (94.2), Nat Rev Cancer 2019 (92.2), and NEJM 2021 (93.0)”,“CrossRef query included full bibliographic strings: title + journal + year + volume + pages + first author”,“Match score threshold of ~70 separates correct DOIs from mismatches or alternative versions”]



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